Molecular Evolution and Phylogenetics [Format Kindle] Author: Masatoshi Nei | Language: English | ISBN:
B0052XUFOG | Format: PDF, EPUB
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Présentation de l'éditeur
During the last ten years, remarkable progress has occurred in the study of molecular evolution. Among the most important factors that are responsible for this progress are the development of new statistical methods and advances in computational technology. In particular, phylogenetic analysis of DNA or protein sequences has become a powerful tool for studying molecular evolution. Along with this developing technology, the application of the new statistical and computational methods has become more complicated and there is no comprehensive volume that treats these methods in depth. Molecular Evolution and Phylogenetics fills this gap and present various statistical methods that are easily accessible to general biologists as well as biochemists, bioinformatists and graduate students. The text covers measurement of sequence divergence, construction of phylogenetic trees, statistical tests for detection of positive Darwinian selection, inference of ancestral amino acid sequences, construction of linearized trees, and analysis of allele frequency data. Emphasis is given to practical methods of data analysis, and methods can be learned by working through numerical examples using the computer program MEGA2 that is provided.
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Molecular Phylogenetics and Evolution Journal Elsevier Molecular Phylogenetics and Evolution is dedicated to bringing Darwin s dream within grasp to have fairly true genealogical trees of each great kingdom of Nature Molecular Evolution and Phylogenetics 9780195135855 Molecular Evolution and Phylogenetics and over one million other books are available for Amazon Kindle Learn moreMolecular Phylogenetics and Evolution ScienceDirect com The online version of Molecular Phylogenetics and Evolution at ScienceDirect com the world s leading platform for high quality peer reviewed full text journals Molecular Evolution and Phylogenetics CH 1 CH 2 CH 3 CH 4 CH 5 CH 6 CH 7 CH 8 CH 9 CH 10 CH 11 CH 12 CH 13 CH 14 OVERVIEW LINKS ERRATA HOME Contact Webmaster Revised
Ce livre est absolument génial. Etudiant en biologie j'ai eu besoin d'approfondir certaines notions en phylogénie pour un stage. Je m'en suis donc servit. Il est clair, concis, et renvoit à des références précises pour pousser la réflection plus loin. Certes il est en anglais mais le style est limpide ce qui fait qu'on oublie vite la barrière du langage au bout de quelques minutes de lecture. A mettre dans toutes les mains des intéressés par la phylogénie.
Par Philippe Fortuné
Nei and Kumar's "Molecular Evolution and Phylogenetics" is basically an updated version of Nei's 1987 "Molecular Evolutionary Genetics" book. Accordingly, attention is shifted to reviewing many recent advances in methods of phylogenetic inference with an obvious bias towards distance methods, particularly those which the senior author devised. In fairness, they give decent coverage to the more popular parsimony and likelihood methods as well. The great strength of the book is the number of real examples used to illustrate properties of the methods, and their focus on statistical methodology without miring the reader in detailed mathematics. The disappointment is that while breadth of coverage is tolerable, depth is lacking. Expanding their views on the shortcomings of likelihood in choosing tree topology and likelihood ratio-tests in choosing models of sequence evolution would have been most enlightening, particularly as these issues have been brushed lightly aside by phylo-likelihoodists. Other methods (Hadamard transformations, Bayesian phylogenetic inference) were absent altogether. Further the chapter on molecular clocks was disappointing--old 1980s controversies were rehashed, while there was nothing on methods that relax the assumption of rate constancy while still allowing divergences to be dated. Admittedly some of this is very new and research is ongoing, but there isn't even a hint of these developments in this chapter. Another plus though is the addition of a chapter on inferring ancestral states of molecular sequences.
Unlike Molecular Evolutionary Genetics, far too little of the book is devoted to methods at the population level, and what is there again smacks of state-of-the-art 15-20 years ago. I was hoping for much more coverage of microsatellite and AFLP data. There was very little for either, while now rarely-used RFLPs were given extensive coverage.
In short, this book was too short, particularly for the price, and I almost gave it 3 stars rather than 4. However, if you are a phylogeneticist, you will probably want to have this book on your shelf. A lighter introduction for the uninitiated would be Rod Page's "Molecular Evolution" or Graur and Li's "Fundamentals of Molecular Evolution". However, my hopes for a good comprehensive text and reference on phylogenetic methods now rest on publication of Joseph Felsenstein's "Inferring Phylogenies".
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